MGF Dosage, Protocol, and Reconstitution Guide

MGF

MGF, or mechano growth factor, is a splice variant of IGF-1 associated with muscle repair and local recovery signaling after training or mechanical stress. It is commonly discussed for short-term repair support and satellite cell activity.

How It Works

Mechanical Stress Signal → Satellite Cell Activation ↑ → Local Repair Support ↑ → Recovery

MGF is associated with the local repair response that follows muscle damage or intense training. Compared with PEG-MGF, native MGF is shorter-acting and is generally discussed in shorter, more targeted recovery protocols.

MGF Protocol

Weeks 1–2

Dose100 mcg

Units10 units (0.10 mL)

Frequency3x weekly

Weeks 3–4

Dose150 mcg

Units15 units (0.15 mL)

Frequency3x weekly

Weeks 5–6

Dose200 mcg

Units20 units (0.20 mL)

Frequency3x weekly

Frequency: 2–3 times weekly
Timing: Commonly post-workout or on recovery days
Cycle Length: 4–6 weeks

Advanced Protocol

Higher Range

Dose200–300 mcg per injection

Because native MGF is shorter-acting, it is usually discussed as a shorter-cycle, more frequent-use peptide rather than a long-duration weekly protocol like PEG-MGF.

When & Where to Use

• Subcutaneous or intramuscular use is commonly discussed
• Often used post-training
• Some users prefer localized intramuscular use near trained muscle groups
• Rotate injection sites consistently

Reconstitution & Dosing (2 mg Vial)

Vial 2 mg

Water 2.0 mL

Concentration 1 mg/mL

Conversion 1 unit = 10 mcg

Reconstitution Steps

Draw 2.0 mL bacteriostatic water

Inject slowly down vial wall

Gently swirl (do not shake)

Refrigerate immediately

Storage

Lyophilized: refrigerated or frozen

Reconstituted: 2–8°C

Use Window

Use within ~3–4 weeks

Monitoring During Use

• Recovery speed and soreness
• Training output
• Localized muscle response
• Injection site tolerance

Benefits

• Supports local muscle repair signaling
• May enhance recovery after training
• Associated with satellite cell activation
• Useful in shorter recovery-focused protocols

Potential Side Effects

• Injection site irritation
• Mild soreness or swelling
• Very limited human safety data

Stacking Strategies

• Recovery: MGF + BPC-157
• Growth / Repair: MGF + IGF-1 LR3
• Comparison Option: Use PEG-MGF instead for longer activity

Important Notes

• Shorter-acting than PEG-MGF
• Often used in shorter cycles
• Usually discussed in muscle repair and post-training contexts
• Human evidence remains limited

Important Disclaimer

MGF is not FDA-approved and is intended for research purposes only.

Peptide Directory →