GHRP-2 Dosage, Protocol, and Reconstitution Guide

GHRP-2

GHRP-2 is a synthetic growth hormone secretagogue that binds to the ghrelin receptor and stimulates pulsatile GH release. It is commonly discussed for growth hormone support, recovery, fat metabolism, and body composition, but it is generally considered less selective than Ipamorelin.

How It Works

Ghrelin Receptor Activation → GH Pulse ↑ → IGF-1 ↑ → Recovery + Fat Loss + Appetite ↑

GHRP-2 activates the growth hormone secretagogue receptor (GHSR-1a), producing a short GH pulse and downstream IGF-1 support. Compared with Ipamorelin, it is more likely to increase appetite and may produce mild stimulation of prolactin, ACTH, and cortisol.

GHRP-2 Protocol

Weeks 1–2

Dose100 mcg

Units6 units (0.06 mL)

Weeks 3–4

Dose150 mcg

Units10 units (0.10 mL)

Weeks 5–8

Dose200 mcg

Units12 units (0.12 mL)

Weeks 9–12

Dose250 mcg

Units16 units (0.16 mL)

Frequency: Once daily
Timing: 30–60 min before bed, often fasted
Cycle Length: 8–12 weeks (optional 16 weeks + break)

Advanced Protocol

Higher Range

Dose200–300 mcg daily

Some protocols split dosing into AM + PM pulses, but once-daily bedtime use is the cleaner starting point for most structured protocols.

When & Where to Inject

• Subcutaneous injection
• Abdomen, thigh, or upper arm
• Often used fasted for cleaner GH signaling
• Rotate injection sites consistently

Reconstitution & Dosing (5 mg Vial)

Vial 5 mg

Water 3.0 mL

Concentration 1.67 mg/mL

Conversion 1 unit = 16.7 mcg

Reconstitution Steps

Draw 3.0 mL bacteriostatic water

Inject slowly down vial wall

Gently swirl (do not shake)

Refrigerate immediately

Storage

Lyophilized: refrigerated or frozen

Reconstituted: 2–8°C

Use Window

Use within ~4 weeks

Monitoring During Use

• Sleep quality
• Recovery and soreness
• Body composition changes
• Appetite response
• IGF-1 levels on longer cycles

Benefits

• Increased natural GH release
• Improved recovery and repair
• Supports fat metabolism
• May support lean mass retention
• Can enhance appetite in some users

Potential Side Effects

• Mild injection site irritation
• Noticeable hunger increase
• Temporary water retention
• Headache or flushing
• Mild cortisol / prolactin activity compared with more selective peptides

Stacking Strategies

• Classic Stack: GHRP-2 + CJC-1295 (NO DAC)
• Recovery: GHRP-2 + BPC-157
• Mass / Recovery: GHRP-2 + IGF-1 LR3

Important Notes

• Less selective than Ipamorelin
• More likely to increase appetite
• Short-acting pulse makes timing matter
• Works best with good sleep, training, and nutrition

Important Disclaimer

GHRP-2 is not FDA-approved and is intended for research purposes only.

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