CJC-1295 (NO DAC) + Ipamorelin Dosage, Protocol, and Reconstitution Guide
CJC-1295 (NO DAC) + Ipamorelin
This combination pairs a growth hormone releasing hormone peptide with a growth hormone secretagogue to create a stronger natural GH pulse. It is one of the most commonly discussed GH support combinations for recovery, body composition, sleep, and lean mass support.
How It Works
GHRH Signal (CJC-1295) + Ghrelin Signal (Ipamorelin) → GH Pulse ↑↑ → IGF-1 ↑ → Recovery + Fat Loss + Lean Mass Support
CJC-1295 (NO DAC) stimulates the pituitary through GHRH pathways, while Ipamorelin activates the ghrelin receptor. Together, they create a stronger pulsatile growth hormone response than either peptide alone.
Protocol
Blended Vial Protocol
Blend: 5 mg CJC-1295 + 5 mg Ipamorelin
Add 3.0 mL bacteriostatic water
Each peptide concentration = 1.67 mg/mL
1 unit = 16.7 mcg CJC-1295 + 16.7 mcg Ipamorelin
1 unit = about 33 mcg total combined
Weeks 1–2
Dose100 mcg of each peptide
Combined Total200 mcg total
Units6 units
Weeks 3–4
Dose150 mcg of each peptide
Combined Total300 mcg total
Units9 units
Weeks 5–8
Dose200 mcg of each peptide
Combined Total400 mcg total
Units12 units
Weeks 9–12
Dose250 mcg of each peptide
Combined Total500 mcg total
Units15 units
Separate Vials Protocol
Use 1 vial of CJC-1295 (5 mg) and 1 vial of Ipamorelin (5 mg)
Add 3.0 mL bacteriostatic water to each vial
1 unit from each vial = 16.7 mcg
Weeks 1–2
CJC-12956 units (100 mcg)
Ipamorelin6 units (100 mcg)
Combined Total200 mcg total
Weeks 3–4
CJC-12959 units (150 mcg)
Ipamorelin9 units (150 mcg)
Combined Total300 mcg total
Weeks 5–8
CJC-129512 units (200 mcg)
Ipamorelin12 units (200 mcg)
Combined Total400 mcg total
Weeks 9–12
CJC-129515 units (250 mcg)
Ipamorelin15 units (250 mcg)
Combined Total500 mcg total
How to Inject
Draw both peptides into the same syringe
Inject once daily before bed
Advanced Protocol (Morning + Night)
Weeks 1–2
MorningCJC-1295: 50 mcg + Ipamorelin: 50 mcg
NightCJC-1295: 100 mcg + Ipamorelin: 100 mcg
Daily Total150 mcg each
Weeks 3–4
MorningCJC-1295: 100 mcg + Ipamorelin: 100 mcg
NightCJC-1295: 100 mcg + Ipamorelin: 100 mcg
Daily Total200 mcg each
Weeks 5–8
MorningCJC-1295: 100 mcg + Ipamorelin: 100 mcg
NightCJC-1295: 150 mcg + Ipamorelin: 150 mcg
Daily Total250 mcg each
Weeks 9–12
MorningCJC-1295: 150 mcg + Ipamorelin: 150 mcg
NightCJC-1295: 150 mcg + Ipamorelin: 150 mcg
Daily Total300 mcg each
Morning: Fasted (or at least 2–3 hours after eating)
Night: 30–60 minutes before bed (fasted)
Why split dosing: Mimics natural GH pulsatility and may enhance total daily GH output
When & Where to Inject
- Subcutaneous injection
- Abdomen, thigh, or upper arm
- Best used fasted before sleep
- Rotate injection sites consistently
Reconstitution & Dosing (Blended Vial)
Vial
5 mg CJC-1295 + 5 mg Ipamorelin
Water
3.0 mL
Concentration
1.67 mg/mL (each peptide)
Conversion
1 unit = 16.7 mcg CJC + 16.7 mcg Ipamorelin
Reconstitution Steps
Draw 3.0 mL bacteriostatic water
Inject slowly down the vial wall
Gently swirl (do not shake)
Allow powder to fully dissolve
Storage
Store lyophilized vial refrigerated or frozen
After mixing: keep refrigerated (2–8°C)
Protect from light and avoid shaking
Use Window
Use within ~4 weeks after reconstitution
Monitoring During Use
- Sleep quality and deep sleep response
- Recovery and soreness
- Body composition changes
- IGF-1 levels on longer cycles
Benefits
- Synergistic GH release
- Improved recovery and tissue repair
- Enhanced fat metabolism
- Lean muscle support
- Better sleep quality
Potential Side Effects
- Mild injection site irritation
- Headache (rare)
- Water retention
- Temporary hunger increase
Stacking Strategies
- Recovery: Add BPC-157
- Advanced: Add IGF-1 LR3
- Body Composition: Pair with disciplined sleep, training, and nutrition
Important Notes
- This is one of the most commonly used GH peptide combinations
- Blended and separate setups can produce the same dose outcome
- 100 mcg each = 200 mcg combined total
- Consistency matters more than aggressive dosing
Important Disclaimer
CJC-1295 (NO DAC) and Ipamorelin are not FDA-approved and are intended for research purposes only.
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