GHK-Cu Peptide: Dosage, Protocol, Reconstitution, and Skin & Hair Regeneration Guide
GHK-Cu Peptide
GHK-Cu (glycyl-L-histidyl-L-lysine:copper complex) is a naturally occurring copper peptide involved in wound healing, tissue remodeling, collagen synthesis, and anti-inflammatory signaling. Research shows it influences gene expression related to regeneration, antioxidant defense, and skin repair.
How GHK-Cu Works
Collagen ↑ → Tissue Repair ↑ → Inflammation ↓ → Skin & Hair Regeneration ↑
- Activates collagen and elastin production pathways
- Enhances wound healing and tissue remodeling
- Reduces oxidative stress and inflammation
- Stimulates hair follicle activity
- Improves skin thickness and elasticity
Reconstitution & Dosing (50 mg Vial)
Precision Dosing → Consistent Injection → Optimal Tissue Response
Vial50 mg
Water3.0 mL bacteriostatic
Concentration16.67 mg/mL
Conversion1 unit = 167 mcg
Common Conversions
1 mg = 6 units (0.06 mL)
1.5 mg = 9 units (0.09 mL)
2 mg = 12 units (0.12 mL)
Reconstitution Steps
Draw 3.0 mL bacteriostatic water
Inject slowly down vial wall
Gently swirl (do not shake)
Refrigerate immediately
Protect from light
Standard Protocol (5 Days / Week)
Weeks 1–4
Dose1.0 mg (1000 mcg)
Units6 units
Volume0.06 mL
Assess Tolerance
Weeks 5–8
Dose1.5 mg (1500 mcg)
Units9 units
Volume0.09 mL
Increased Response
Weeks 9–12+
Dose2.0 mg (2000 mcg)
Units12 units
Volume0.12 mL
Full Protocol
Frequency: Once daily, 5 days per week (subcutaneous)
Alternative Protocol (3× Weekly)
Weeks 1–12+
Dose2.0 mg (2000 mcg)
Units12 units
Volume0.12 mL
Frequency3× weekly
Benefits
- Improves skin elasticity and reduces wrinkles
- Enhances wound healing and recovery
- Promotes hair growth and follicle health
- Reduces inflammation and oxidative stress
- Supports long-term tissue regeneration
Side Effects
- Possible skin irritation (topical use)
- Temporary redness or sensitivity
- Rare systemic effects
Stacking Strategies
GHK-Cu → Collagen & Tissue Repair
BPC-157 → Healing & Blood Flow
TB-500 → Systemic Recovery
- Skin: GHK-Cu + microneedling / topical routine
- Healing: GHK-Cu + BPC-157
- Advanced: GHK-Cu + BPC-157 + TB-500
Storage
- Lyophilized: −20°C (−4°F)
- Reconstituted: 2–8°C (36–46°F)
- Use within 30 days
Important Notes
- Dosing varies by goal (cosmetic vs healing)
- Lower doses effective for skin applications
- Higher doses used for injury repair
- Protocols based on clinical practice patterns
Important Disclaimer
GHK-Cu is investigational and not FDA-approved. Educational use only.
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