AOD-9604 Dosage, Protocol, and Fat Loss Guide (Non-Hormonal hGH Fragment)

AOD-9604 Peptide

AOD-9604 is a synthetic fragment of human growth hormone (hGH 177–191) designed to promote fat loss by stimulating lipolysis and inhibiting lipogenesis—without increasing IGF-1 or impacting insulin sensitivity.

How AOD-9604 Works

Fat Cell Targeting → Lipolysis ↑ → Lipogenesis ↓ → Fat Mass ↓

AOD-9604 binds directly to adipose tissue, triggering fat breakdown while blocking fat storage. Unlike full hGH, it does not significantly affect IGF-1 or glucose metabolism, making it one of the most metabolically neutral fat-loss peptides studied.

AOD-9604 Protocol

Weeks 1–4

Dose300 mcg daily

Units18 units (0.18 mL)

Weeks 5–12

Dose500 mcg daily

Units30 units (0.30 mL)

Frequency: Once daily
Timing: Morning (fasted preferred)
Cycle Length: 8–12 weeks (optional 16-week extension)

Clinical vs Real-World Dosing

• 300–500 mcg: Common real-world range
• 1 mg daily: Used in clinical trials
• Clinical data shows modest but consistent fat loss over 12 weeks

When & Where to Inject

• Subcutaneous injection
• Abdomen, thighs, or upper arms
• Morning dosing (fasted) preferred
• Rotate injection sites daily

Reconstitution & Dosing (5 mg Vial)

Vial 5 mg

Water 3.0 mL bacteriostatic

Concentration 1.667 mg/mL

Conversion 1 unit = 16.67 mcg

Reconstitution Steps

Draw 3.0 mL bacteriostatic water

Inject slowly down vial wall

Gently swirl (do not shake)

Refrigerate immediately

Storage

Lyophilized: −20°C (−4°F)

Reconstituted: 2–8°C (36–46°F)

Use Window

Use within 3–4 weeks

Supply Planning (8–16 Weeks)

• 8 weeks: ~5 vials (5 mg each)
• 12 weeks: ~8 vials
• 16 weeks: ~11 vials
• Syringes: 1 per day (56–112 total)
• Bacteriostatic water: 2–4 bottles (10 mL)

Monitoring During Use

• Body weight and fat loss
• Waist circumference
• Energy levels
• No significant IGF-1 monitoring typically required

Benefits

• Promotes fat loss (especially abdominal)
• Increases fat oxidation
• Does not elevate IGF-1
• Does not impair glucose tolerance
• Well-tolerated (placebo-like safety profile)

Potential Side Effects

• Mild injection site irritation
• Rare redness or itching
• Minimal systemic side effects reported

Stacking Strategies

• Fat Loss: AOD-9604 + GLP-1 (Tirzepatide / Semaglutide)
• Advanced: AOD-9604 + Tesamorelin
• Metabolic: AOD-9604 + NAD+

Important Notes

• Works best with calorie control and exercise
• Not a standalone weight-loss solution
• Effects are gradual and cumulative

Important Disclaimer

AOD-9604 is not FDA-approved. This content is for educational purposes only.

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